Nos projets

Grâce à nos donatrices et donateurs, 21 projets de recherche bénéficient actuellement d’un soutien dans des universités et instituts de recherche de Suisse. Tous ont pour but d’approfondir la compréhension de la maladie d’Alzheimer et d’autres maladies neurodégénératives à toutes les phases de leur évolution:

Prof. Camilla Bellone, Université de Lausanne, «Early synaptic dysfunction in HD model: role of GluN3A»
Prof. Amadeo Caflish, Universität Zürich: “Targeted reverse chemical genetics approach to study the role of CREBBP/p300 in Alzheimer’s disease”
PD Dr. Jean-Yves Chatton, Université de Lausanne, «Using uncoupling in mitochondria of astrocytes to promote neuroprotection in Alzheimer's disease»
Prof. Jean-Francois Démonet, Centre Leenaards de la Mémore, CHUV, «New ocular biomarkers for early detection of Alzheimer's disease»
Dr. Maria Soledad Esposito, Friedrich Miescher Institut Basel, «Cause and consequence of Parkinson's disease in the midbrain locomotor command center»
Dr. Maria Teresa Ferretti, Universität Zürich, «Impaired immune surveillance in Alzheimer's disease: studies on pre-clinical transgenic models and patient-derived samples»
Prof. Johannes Gräf, Brain Mind Institute, EPFL Lausanne, «Traces towards dementia: Identifying neuronal subpopulations and pathogenic mechanisms at presymptomatic stages of Alzheimer's disease in a new mouse model»
Prof. Fritjof Helmchen, Universität Zürich, «Imaging corticostriatal loop dysfunction during skilled locomotion of Parkinsonian mice»
Dr. Annika Keller, Universitätsspital Zürich, «Elucidating the pathogenic mechanism of small vessel calcification in idiopathic basal ganglia calcification»
Prof. Jan Klohs, Universität Zürich und ETH Zürich, «The factor XII-driven contact system as a new therapeutic target in Alzheimer's disease»
Dr. Asvin Lakkaraju, Universitätsspital Zürich; «Mechanistic insights into development of prion induced spongiform phenotype and neurotoxicity»
Dr. Paolo Paganetti, Neurocenter of Southern Switzerland: “Nuclear Tau in Health and Disease”
Dr. Rosa Chiara Paolicelli, Universität Zürich: “Synaptic pruning by dysfunctional microglia in the pathogenesis of neurodegeneration”
Prof. Steven T. Proulx, ETH Zürich: ”Impact of lymphatic outflow in the brain during aging and neurodegenerative disorders”
Dr. Kevin Richetin, CHUV Lausanne, «Role of astrocytic mitochondria in the early stages of Alzheimer disease»
Dr. Aiman S. Saab, Universität Zürich: “How glial metabolic support impacts Alzheimer’s disease disease pathophysiology”
Dr. Jose Vicente Sanchez Mut, EPFL: “PM20D1 function in Alzheimer's disease”
Prof. Henning Stahlberg, Universität Basel, «The Structure of Prionoid Tau Strains»
Dr. Silvia Sorce, Universität Zürich: “A novel approach to study the progression of neurodegenerative diseases: investigating the young brain to understand the old”
Prof. Ron Stoop, Universität Lausanne: “Emotion dysregulation in Alzheimer's patients: a new model based on patients with neurodegenerative loss of the amygdala and hormonal regulation related to personality”
Prof. Nicolas Toni, Université de Lausanne, «Role of astrocytes in the regulation of adult neurogenesis and hippocampal-dependent memory in the aged brain»

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